1st Joint Call: FarmResist

This project studies the occupational risks for animal farmers to be colonised with animal-associated resistant bacteria, impact on the faecal microbiota. It was funded under the 1st Call of the Southeast Asia - Europe Joint Funding Scheme for Science and Innovation.
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Animal farming is a worldwide industry, with millions of people involved in the production of animal products every day. Protecting farmed animals from disease and infection is therefore vitally important not only for livestock and consumer wellbeing, but also for those working within the farming industry.

The Project:

The FarmResist project will use a “One Health” approach, to investigate the occupational risk for pig and poultry farmers of of catching animal-associated ESBL-E and colistin-resistant enterobacteria. It is hoped that this research will lead to the development of preventive measures for avoiding the transmission of zoonotic bacteria from animal to farmers, as well as reducing the spread of antibioresistance in the environment.

The Science:

The researchers will study both small family farms and medium-big industrial farms. At each farm, faecal samples of farmers, animals (included pets and rodents) will be collected. The prevalence, genotyping and microbiota diversity will be studied by using both culture-dependent methods, molecular biology and next generation sequencing.

The association between farm parameters and antimicrobial resistance will be analysed in order to propose preventive measures to avoid the transmission of zoonotic bacteria from animal to farmers and to reduce the spread of antibioresistance in the environment.  The influence of faecal carriage of ESBL-E or colistin resistant bacteria on the faecal microbiota of farmers will then also be studied.

The Team:

The FarmResist partners are:

  • Visanu Thamlikitkul, Siriraj Hospital, Mahidol University.
  • Suwit Chotinun, Chiang Mai University, poultry clinic.
  • Morand Serge, Kasetsart University, Bangkok, Faculty Veterinary Technology
  • Jean-Marc Rolain, URMITE- IHU Méditerranée Infection, Valorization and Transfer, Marseille, France
  • Morand Serge, CNRS- Cirad, France
  • Markus Hilty, IFIK, Bern University, Switzerland
  • Oppliger Anne, IST, Lausanne University, Switzerland


Anne Oppliger: